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AZD0837

Chemical Structure : AZD0837

CAS No.: 433937-93-0

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AZD0837 (Atecegatran metoxil, AZD-0837)

Catalog No.: PC-63163Not For Human Use, Lab Use Only.

Atecegatran metoxil (AZD0837) is an oral anticoagulant that after bioconversion to its active form AR-H067637, which is a potent and reversible thrombin inhibitor.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Atecegatran metoxil (AZD0837) is an oral anticoagulant that after bioconversion to its active form AR-H067637, which is a potent and reversible thrombin inhibitor.

    Physicochemical Properties

    M.Wt 496.896
    Formula C22H23ClF2N4O5
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (S)-1-((R)-2-(3-chloro-5-(difluoromethoxy)phenyl)-2-hydroxyacetyl)-N-(4-(N-methoxycarbamimidoyl)benzyl)azetidine-2-carboxamide

    References

    1. Schützer KM, et al. Eur J Clin Pharmacol. 2010 Sep;66(9):903-10.

    2. Lip GY, et al. Thromb Res. 2011 Feb;127(2):91-9.

    3. Matsson EM, et al. Mol Pharm. 2013 Nov 4;10(11):4252-62.

    4. Deinum J, et al. Thromb Haemost. 2009 Jun;101(6):1051-9.

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