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Chemical Structure : AZD1092
Catalog No.: PC-61877Not For Human Use, Lab Use Only.
AZD1092 (GKA-80) is a potent Glucokinase (GK) activator with EC50 of 30 nM.
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AZD1092 (GKA-80) is a potent Glucokinase (GK) activator with EC50 of 30 nM.
AZD1092 exhibits dose dependent reduction of glucose excursion in oral glucose tolerance tests in high fat fed female Zucker rats.
AZD1092 shows potential for treatment of type 2 diabetes.
| M.Wt | 450.495 | |
| Formula | C24H26N4O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Coope GJ, et al. Br J Pharmacol. 2006 Oct;149(3):328-35.
2. Michael J. Waring, et al. Med. Chem. Commun., 2011, 2, 775-779
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