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Chemical Structure : AZD1656
CAS No.: 919783-22-5
Catalog No.: PC-49824Not For Human Use, Lab Use Only.
AZD1656 (AZD-1656) is a potent, selective and orally active glucokinase (GK) activator with EC50 of 57 and 72 nM for human and rat GK, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $498 | In stock | |
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| 100 mg | Get quote |
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AZD1656 (AZD-1656) is a potent, selective and orally active glucokinase (GK) activator with EC50 of 57 and 72 nM for human and rat GK, respectively.
AZD1656 displays >100-fold versus hexokinase 1 and hexokinase2 in a pharmacology screening panel.
AZD1656 reduced plasma glucose levels in a dose-dependent fashion. with a rapid onset of action, in normo-glycaemic insulin resistant rats and diabetic mice.
| M.Wt | 478.51 | |
| Formula | C24H26N6O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(S)-3-((5-(azetidine-1-carbonyl)pyrazin-2-yl)oxy)-5-((1-methoxypropan-2-yl)oxy)-N-(5-methylpyrazin-2-yl)benzamide |
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1. Norjavaara E, et al. J Clin Endocrinol Metab. 2012 Sep;97(9):3319-25.
2. Morrow LA, et al. Diabetes Obes Metab. 2012 Dec;14(12):1114-22.
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