Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : AZD2716
Catalog No.: PC-60457Not For Human Use, Lab Use Only.
AZD2716 (AZD-2716) is a novel potent, selective, orally bioavailable sPLA2 inhibitor with excellent plasma sPLA2 inhibition (IC50=0.1 nM).
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
AZD2716 (AZD-2716) is a novel potent, selective, orally bioavailable sPLA2 inhibitor with excellent plasma sPLA2 inhibition (IC50=0.1 nM).
AZD2716 effectively inhibits sPLA2 activity (IC50 <14 nM) and suppresses production of sPLA2-IIa (IC50=176 nM), demonstrates significant activity (IC50=56 nM) in atherosclerotic plaque homogenates.
AZD2716 is a clinical candidate for the treatment of coronary artery disease.
| M.Wt | 373.452 | |
| Formula | C24H23NO3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Giordanetto F, et al. ACS Med Chem Lett. 2016 Aug 9;7(10):884-889.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
