AZD2932 | PDGFRβ inhibitor | Probechem Biochemicals

Chemical Structure : AZD2932

CAS No.: 883986-34-3

AZD2932 (AZD-2932)

Catalog No.: PC-45430Not For Human Use, Lab Use Only.

AZD2932 is a potent multikinase inhibitor that inhibits PDGFRβ, VEGFR-2, Flt-3 and CSF-1R with IC50 of 4, 8, 100, and 7 nM, respectively.

Packing	Price	Stock
10 mg	$88	In stock
25 mg	$138	In stock
50 mg	$228	In stock
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Biological Activity

AZD2932 is a potent multikinase inhibitor that inhibits PDGFRβ, VEGFR-2, Flt-3 and CSF-1R with IC50 of 4, 8, 100, and 7 nM, respectively.
AZD2932 shows tumor growth inhibition in in vivo model; orally bioavailable.

Physicochemical Properties

M.Wt	447.4864
Formula	C24H25N5O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 41 mg/mL
Chemical Name/SMILES	Benzeneacetamide, 4-[(6,7-dimethoxy-4-quinazolinyl)oxy]-N-[1-(1-methylethyl)-1H-pyrazol-4-yl]-

References

1. Plé PA, et al. Bioorg Med Chem Lett. 2012 Jan 1;22(1):262-6.

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AZD2932 (AZD-2932)

Biological Activity

Physicochemical Properties

References

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