Chemical Structure : AZD2932
CAS No.: 883986-34-3
Catalog No.: PC-45430Not For Human Use, Lab Use Only.
AZD2932 is a potent multikinase inhibitor that inhibits PDGFRβ, VEGFR-2, Flt-3 and CSF-1R with IC50 of 4, 8, 100, and 7 nM, respectively.
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AZD2932 is a potent multikinase inhibitor that inhibits PDGFRβ, VEGFR-2, Flt-3 and CSF-1R with IC50 of 4, 8, 100, and 7 nM, respectively.
AZD2932 shows tumor growth inhibition in in vivo model; orally bioavailable.
M.Wt | 447.4864 | |
Formula | C24H25N5O4 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 41 mg/mL |
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Chemical Name/SMILES |
Benzeneacetamide, 4-[(6,7-dimethoxy-4-quinazolinyl)oxy]-N-[1-(1-methylethyl)-1H-pyrazol-4-yl]- |
1. Plé PA, et al. Bioorg Med Chem Lett. 2012 Jan 1;22(1):262-6.
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