Chemical Structure : AZD5718
CAS No.:
2041075-86-7
AZD5718
(AZD-5718, Atuliflapon)
Catalog No. : PC-36134Not For Human Use, Lab Use Only.
Atuliflapon (AZD-5718, AZD5718) is a novel potent 5-lipoxygenase activating protein (FLAP) inhibitor with binding IC50 of 6.3 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-3613401
Biological Activity
Atuliflapon (AZD-5718, AZD5718) is a novel potent 5-lipoxygenase activating protein (FLAP ) inhibitor with binding IC50 of 6.3 nM.
Physicochemical Properties
M.Wt
446.511
Formula
C24H26N6O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(1R,2R)-2-[4-(3-Methyl-1H-pyrazol-5-yl)benzoyl]-N-(4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-3-yl)cyclohexanecarboxamide
References
1. Ericsson H, et al. Clin Transl Sci.
2. Pettersen D, et al. J Med Chem.
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