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Chemical Structure : AZD7009
Catalog No.: PC-63155Not For Human Use, Lab Use Only.
AZD7009 is an antiarrhythmic agent that inhibits the late sodium current in CHO K1 cells expressing hNav1.5 with IC50 of 11 uM.
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AZD7009 is an antiarrhythmic agent that inhibits the late sodium current in CHO K1 cells expressing hNav1.5 with IC50 of 11 uM.
AZD7009 also inhibits late sodium current in isolated rabbit atrial and ventricular myocytes, attenuates the E-4031-induced action potential duration prolongation, induces early afterdepolarisations (EADs) in Purkinje fibres.
| M.Wt | 446.548 | |
| Formula | C23H34N4O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Goldstein RN, et al. J Cardiovasc Electrophysiol. 2004 Dec;15(12):1444-50.
2. Persson F, et al. J Cardiovasc Electrophysiol. 2005 Mar;16(3):329-41.
3. Persson F, et al. J Cardiovasc Pharmacol. 2005 Jul;46(1):7-17.
4. Persson F, et al. Eur J Pharmacol. 2007 Mar 8;558(1-3):133-43.
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