Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : AZD8154
Catalog No.: PC-38686Not For Human Use, Lab Use Only.
AZD8154 is a highly potent, selective dual PI3Kγ/δ inhibitor with cell pIC50 of 9.1/8.4, respectively.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
AZD8154 is a highly potent, selective dual PI3Kγ/δ inhibitor with cell pIC50 of 9.1/8.4, respectively.
AZD8154 inhibits the release of IL-5 and IL-17, and eotaxin-3 (CCL26)-induced CD11b expression in peripheral blood mononuclear cells (PBMCs).
AZD8154 inhibits eosinophil migration in response to an inhaled ovalbumin challenge of allergic asthma model.
| M.Wt | 551.680 | |
| Formula | C27H29N5O4S2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Perry MWD, et al. J Med Chem. 2021 Jun 24;64(12):8053-8075.
2. Sadiq MW, et al. Br J Clin Pharmacol. 2022 Jan;88(1):260-270.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
