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Chemical Structure : AZD 8329
CAS No.: 1048668-70-7
Catalog No.: PC-62766Not For Human Use, Lab Use Only.
AZD8329 is a potent, selective 11β-HSD1 inhibitor with IC50 of 9 nM, displays excellent selectivity versus relatedd 11β-HSD2, 17β-HSD1 and 17β-HSD3 (IC50>30 uM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $498 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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AZD8329 is a potent, selective 11β-HSD1 inhibitor with IC50 of 9 nM, displays excellent selectivity versus relatedd 11β-HSD2, 17β-HSD1 and 17β-HSD3 (IC50>30 uM).
AZD8329 shows significantly reduced acyl glucuronidation liability compared with AZD4017.
| M.Wt | 421.541 | |
| Formula | C25H31N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic acid |
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1. Scott JS, et al. J Med Chem. 2012 Nov 26;55(22):10136-47.
2. Morentin Gutierrez P, et al. Br J Pharmacol. 2015 Oct;172(20):4806-16.
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