AZD9164 |CAS:1194737-07-9 Probechem Biochemicals

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Chemical Structure : AZD9164

AZD9164 (AZD 9164;AZD-9164)

Catalog No.: PC-61047Not For Human Use, Lab Use Only.

AZD9164 is a highly potent, selective, long acting muscarinic receptor M3 antagonist with pIC50 of 9.8, 10-fold selectivity over M2 (pIC50=9.0).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

AZD9164 is a highly potent, selective, long acting muscarinic receptor M3 antagonist with pIC50 of 9.8, 10-fold selectivity over M2 (pIC50=9.0).
AZD9164 demonstrates potential as a treatment for COPD.

Physicochemical Properties

M.Wt	465.633
Formula	C29H38FN2O2+
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-1-(4-fluorophenethyl)-3-(((S)-2-phenyl-2-(piperidin-1-yl)propanoyl)oxy)quinuclidin-1-ium

References

1. Mete A, et al. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6248-53.

2. Bjermer L, et al. Respir Med. 2013 Jan;107(1):84-90.

3. Mastrodicasa MA, et al. Expert Opin Investig Drugs. 2017 Feb;26(2):161-174.

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AZD9164 (AZD 9164;AZD-9164)

Biological Activity

Physicochemical Properties

References

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