Abciximab |CAS:143653-53-6 Probechem Biochemicals

Chemical Structure : Abciximab

CAS No.:

Abciximab (Anti-human GPIIb/IIIa mAb, human IgG1 Fab-Kappa; c7E3 Fab)

Catalog No.: PC-Ab1095Not For Human Use, Lab Use Only.

Abciximab (Abcixifiban.

Packing	Price	Stock
1 mg	$358	In stock
5 mg	$758	In stock
10 mg	$1280	In stock
100 mg		Get quote

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Biological Activity

Abciximab (Abcixifiban; c7E3 Fab) is a monoclonal anti-glycoprotein IIb/IIIa receptor antibody antagonist, prevents platelet aggregation by blocking glycoprotein IIb/IIIa receptors on their platelet's plasma membrane and inhibits fibrinogen binding. It exerts it`s action by steric hindrance of the receptor itself and prevents platelet aggregation and subsequent thrombus formation and blocking interaction of fibrinogen. It also inhibits vitronectin receptor which mediates both platelet coagulation as well as endothelial and vascular smooth muscle proliferation.

Physicochemical Properties

M.Wt
Formula	Human IgG1 Fab-Kappa
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

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Abciximab (Anti-human GPIIb/IIIa mAb, human IgG1 Fab-Kappa; c7E3 Fab)

Biological Activity

Physicochemical Properties

References

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