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Adintrevimab

Chemical Structure : Adintrevimab

CAS No.:

Adintrevimab (ADG20)

Catalog No.: PC-38888Not For Human Use, Lab Use Only.

Adintrevimab (ADG20) is a fully human IgG1 monoclonal antibody targeting the highly conserved epitope on the receptor-binding domain (RBD) of S (spike) protein of SARS-CoV-2.

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    Biological Activity

    Adintrevimab (ADG20) is a fully human IgG1 monoclonal antibody targeting the highly conserved epitope on the receptor-binding domain (RBD) of S (spike) protein of SARS-CoV-2.
    Adintrevimab (ADG20) demonstrated an ability to potently neutralize SARS-CoV-2, including variants of concern, as well as a broad range of sarbecoviruses.
    Adintrevimab (ADG20) exhibited broadly neutralizing the entire clade of SARS-like viruses from the sarbecovirus lineage, including diverse family members such as SARS-CoV-1, WIV1, SHC014 and SARS-CoV-2.

    Isotype: IgG1-lambda2.
    Anti-[human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein, receptor binding domain (RBD)], human monoclonal antibody.

    Physicochemical Properties

    M.Wt
    Formula
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    References

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