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AdipoR1 agonist P5

Chemical Structure : AdipoR1 agonist P5

CAS No.: 1013053-78-5

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AdipoR1 agonist P5 (GLYYF)

Catalog No.: PC-38839Not For Human Use, Lab Use Only.

AdipoR1 agonist P5 (GLYYF) is a pentapeptide agonist of adiponectin receptor 1 (AdipoR1), promotes hair growth.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    AdipoR1 agonist P5 (GLYYF) is a pentapeptide agonist of adiponectin receptor 1 (AdipoR1), promotes hair growth.
    P5 sufficiently reproduces the biological effect of adiponectin protein via AMPK signaling pathway, increasing the expression of hair growth factors in the dermal papilla cells of human hair follicle.
    P5 accelerates hair growth ex vivo and induces anagen hair cycle in mice in vivo.

    Physicochemical Properties

    M.Wt 661.756
    Formula C35H43N5O8
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    glycyl-L-leucyl-L-tyrosyl-L-tyrosyl-L-phenylalanine

    References

    1. Jungyoon Ohn, et al. EMBO Mol Med. 2021 Oct 7;13(10):e13790.

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