Chemical Structure : Adomeglivant
CAS No.:
1488363-78-5
Adomeglivant
(LY-2409021)
Catalog No. : PC-45745Not For Human Use, Lab Use Only.
Adomeglivant (LY-2409021) is a potent, selective, orally active, small-molecule antagonist of human glucagon receptor with Ki of 6.66 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4574501
Biological Activity
Adomeglivant (LY-2409021) is a potent, selective, orally active, small-molecule antagonist of human glucagon receptor with Ki of 6.66 nM.
Physicochemical Properties
M.Wt
555.6277
Formula
C32H36F3NO4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 5.3 mg/mL
Chemical Name/SMILES
β-Alanine, N-[4-[(1S)-1-[[4'-(1,1-dimethylethyl)-2,6-dimethyl[1,1'-biphenyl]-4-yl]oxy]-4,4,4-trifluorobutyl]benzoyl]-
References
1. Kelly RP, et al. Diabetes Obes Metab. 2015 Apr;17(4):414-22.
2. Grover S, et al. BMC Bioinformatics. 2014;15 Suppl 16:S13.
3. Kazda CM, et al. Diabetes Obes Metab. 2017 Aug;19(8):1071-1077.
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