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Aducanumab

Chemical Structure : Aducanumab

CAS No.:

Aducanumab (Anti-huamn amyloid beta mAb, human IgG1(K97R)-Kappa; BIIB 037)

Catalog No.: PC-Ab1059Not For Human Use, Lab Use Only.

Aducanumab (BIIB037) is a human monoclonal antibody selectively targets aggregated Aβ, binds to the N-terminus of Aβ peptide and recognizes aggregated forms of Aβ, including epitopes or conformations present in soluble and insoluble oligomers. The FDA approved aducanumab under accelerated approval based on reduction in amyloid plaques in Alzheimer's disease (AD)..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Aducanumab (BIIB037) is a human monoclonal antibody selectively targets aggregated Aβ, binds to the N-terminus of Aβ peptide and recognizes aggregated forms of Aβ, including epitopes or conformations present in soluble and insoluble oligomers. The FDA approved aducanumab under accelerated approval based on reduction in amyloid plaques in Alzheimer's disease (AD).

Physicochemical Properties

M.Wt
Formula Human IgG1(K97R)-Kappa
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

References

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