Afabicin (Debio 1450, AFN-1720)

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Chemical Structure : Afabicin

CAS No.: 1518800-35-5

Catalog No.: PC-27731Not For Human Use, Lab Use Only.

Afabicin (Debio 1450, AFN-1720) is an antibiotic targets the staphylococcal enoyl-acyl carrier protein reductase (FabI) and exhibits selective potent antibacterial activity against staphylococcal species, including MRSA,

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Biological Activity

Afabicin (Debio 1450, AFN-1720) is an antibiotic targets the staphylococcal enoyl-acyl carrier protein reductase (FabI) and exhibits selective potent antibacterial activity against staphylococcal species, including MRSA,

Physicochemical Properties

M.Wt	485.43
Formula	C23H24N3O7P
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-(6-(3-(methyl((3-methylbenzofuran-2-yl)methyl)amino)-3-oxoprop-1-en-1-yl)-2-oxo-3,4-dihydro-1,8-naphthyridin-1(2H)-yl)methyl dihydrogen phosphate

References

1. Wittke F, et al. Antimicrob Agents Chemother. 2020 Sep 21;64(10):e00250-20.

2. Menetrey A, et al. Antimicrob Agents Chemother. 2019 Feb 26;63(3):e01669-18.

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