Chemical Structure : Alflutinib
CAS No.: 1869057-83-9
Catalog No.: PC-35640Not For Human Use, Lab Use Only.
Alflutinib (Furmonertinib, AST-2818) is a third generation EGFR mutation selective tyrosine kinase inhibitor, inhibits EGFR active mutations as well as T790M acquired resistant mutation.
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Alflutinib (Furmonertinib, AST-2818) is a third generation EGFR mutation selective tyrosine kinase inhibitor, inhibits EGFR active mutations as well as T790M acquired resistant mutation.
| M.Wt | 568.605 | |
| Formula | C28H31F3N8O2 | |
| Appearance | Solid | |
| Storage | 
                            
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| Solubility | 
                             10 mM in DMSO  | 
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| Chemical Name/SMILES | 
                             N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)acrylamide  | 
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1. PCT Int. Appl. (2017), WO 2017152707 A1 20170914.
2. PCT Int. Appl. (2017), WO 2017152706 A1 20170914.

                
                
                
                
                
                
                
                
            
            
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