Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Renin-Aliskiren
Aliskiren

Chemical Structure : Aliskiren

CAS No.: 173334-57-1

Aliskiren (CGP 60536;CGP60536B;SPP 100)

Catalog No.: PC-42905Not For Human Use, Lab Use Only.

Aliskiren (CGP60536B) is a first-in-class, potent and highly selective, direct renin inhibitor with IC50 of 0.6 nM.

Packing Price Stock Quantity
5 mg $68 In stock
10 mg $98 In stock
25 mg $158 In stock
50 mg $248 In stock
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Aliskiren (CGP60536B) is a first-in-class, potent and highly selective, direct renin inhibitor with IC50 of 0.6 nM.
Aliskiren shows no significant inhibition on Cathepsin D, Cathepsin E, Pepsin and HIV-1 peptidase (> 50 uM); orally bioactive.

Physicochemical Properties

M.Wt 551.7583
Formula C30H53N3O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzeneoctanamide, .delta.-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-.gamma.-hydroxy-4-methoxy-3-(3-methoxypropoxy)-.alpha.,.zeta.-bis(1-methylethyl)-, (.alpha.S,.gamma.S,.delta.S,.zeta.S)-

References

1. Wood JM, et al. Biochem Biophys Res Commun. 2003 Sep 5;308(4):698-705.

2. Desjarlais M, et al. Atherosclerosis. 2015 Oct;242(2):450-60.

3. Jumar A, et al. J Hypertens. 2015 Dec;33(12):2491-9.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: