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Chemical Structure : Aliskiren
CAS No.: 173334-57-1
Catalog No.: PC-42905Not For Human Use, Lab Use Only.
Aliskiren (CGP60536B) is a first-in-class, potent and highly selective, direct renin inhibitor with IC50 of 0.6 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $68 | In stock | |
| 10 mg | $98 | In stock | |
| 25 mg | $158 | In stock | |
| 50 mg | $248 | In stock | |
| 100 mg | Get quote |
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Aliskiren (CGP60536B) is a first-in-class, potent and highly selective, direct renin inhibitor with IC50 of 0.6 nM.
Aliskiren shows no significant inhibition on Cathepsin D, Cathepsin E, Pepsin and HIV-1 peptidase (> 50 uM); orally bioactive.
| M.Wt | 551.7583 | |
| Formula | C30H53N3O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Benzeneoctanamide, .delta.-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-.gamma.-hydroxy-4-methoxy-3-(3-methoxypropoxy)-.alpha.,.zeta.-bis(1-methylethyl)-, (.alpha.S,.gamma.S,.delta.S,.zeta.S)- |
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1. Wood JM, et al. Biochem Biophys Res Commun. 2003 Sep 5;308(4):698-705.
2. Desjarlais M, et al. Atherosclerosis. 2015 Oct;242(2):450-60.
3. Jumar A, et al. J Hypertens. 2015 Dec;33(12):2491-9.
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