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Chemical Structure : Aloxistatin
CAS No.: 88321-09-9
Catalog No.: PC-42094Not For Human Use, Lab Use Only.
Aloxistatin (E64d) is an irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases with the ability to inhibit calpain activity in intact platelets.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $88 | In stock | |
| 10 mg | $138 | In stock | |
| 25 mg | $228 | In stock | |
| 50 mg | $388 | In stock | |
| 100 mg | Get quote |
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Aloxistatin (E64d) is an irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases with the ability to inhibit calpain activity in intact platelets.
Aloxistatin (E64d) reduces brain amyloid-β and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B.
| M.Wt | 342.4305 | |
| Formula | C17H30N2O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 23 mg/mL |
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| Chemical Name/SMILES |
2-Oxiranecarboxylic acid, 3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-, ethyl ester, (2S,3S)- |
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1. Ostrowski LE, et al. Cancer Res. 1986 Aug;46(8):4121-8.
2. Hook G, et al. J Alzheimers Dis. 2011;26(2):387-408.
3. McGowan EB, et al. Biochem Biophys Res Commun. 1989 Jan 31;158(2):432-5.
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