Chemical Structure : Alvimopan dihydrate
CAS No.: 170098-38-1
Catalog No.: PC-45977Not For Human Use, Lab Use Only.
Alvimopan (ADL 8-2698, LY246736) dihydrate selective peripherally acting μ-opioid antagonist with IC50 of 1.7 nM for the treatment of postoperative ileus.
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Alvimopan (ADL 8-2698, LY246736) dihydrate selective peripherally acting μ-opioid antagonist with IC50 of 1.7 nM for the treatment of postoperative ileus.
Alvimopan prevents gastrointestinal effects of intravenous morphine without affecting analgesia; orally active.
M.Wt | 460.5631 | |
Formula | C25H36N2O6 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Glycine, N-[(2S)-2-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]-, hydrate (1:2) |
1. Fukuda H, et al. Brain Res. 2006 Aug 2;1102(1):63-70.
2. Taguchi A, et al. N Engl J Med. 2001 Sep 27;345(13):935-40.
3. Schmidt WK. Am J Surg. 2001 Nov;182(5A Suppl):27S-38S.
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