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Chemical Structure : Alvimopan monohydrate
CAS No.: 1383577-62-5
Catalog No.: PC-45976Not For Human Use, Lab Use Only.
A selective peripherally acting μ-opioid antagonist with IC50 of 1.7 nM for the treatment of postoperative ileus.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $193.6 | In stock | |
| 50 mg | $572 | In stock | |
| 250 mg | Get quote |
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A selective peripherally acting μ-opioid antagonist with IC50 of 1.7 nM for the treatment of postoperative ileus; prevents gastrointestinal effects of intravenous morphine without affecting analgesia; orally active.
Other Indication
Approved
| M.Wt | 442.5479 | |
| Formula | C25H34N2O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Glycine, N-[(2S)-2-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]-, hydrate (1:1) |
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1. Fukuda H, et al. Brain Res. 2006 Aug 2;1102(1):63-70.
2. Taguchi A, et al. N Engl J Med. 2001 Sep 27;345(13):935-40.
3. Schmidt WK. Am J Surg. 2001 Nov;182(5A Suppl):27S-38S.
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