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Amatuximab

Chemical Structure : Amatuximab

CAS No.:

Amatuximab (Anti-human MSLN mAb, human IgG1-Kappa; MORAb-009)

Catalog No.: PC-Ab1080Not For Human Use, Lab Use Only.

Mesothelin (MSLN) is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Amatuximab (MORAb-009) blocks the binding of mesothelin to CA 125 and thus could be used also as a strategy to prevent tumor metastasis..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Mesothelin (MSLN) is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Amatuximab (MORAb-009) blocks the binding of mesothelin to CA 125 and thus could be used also as a strategy to prevent tumor metastasis.

Physicochemical Properties

M.Wt
Formula Human IgG1-Kappa
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

References

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