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Ambrisentan

Chemical Structure : Ambrisentan

CAS No.: 177036-94-1

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Ambrisentan (BSF208075, BSF-208075, LU208075, LU-208075)

Catalog No.: PC-43394Not For Human Use, Lab Use Only.

Ambrisentan (BSF 208075, LU 208075) is a highly selective antagonist of the endothelin-1 type A receptor (ETA) for use in the treatment of pulmonary hypertension.

Packing Price Stock Quantity
25 mg $88 In stock
100 mg $158 In stock
500 mg $288 In stock
1 g $398 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Ambrisentan (BSF 208075, LU 208075) is a highly selective antagonist of the endothelin-1 type A receptor (ETA) for use in the treatment of pulmonary hypertension.

Physicochemical Properties

M.Wt 378.4211
Formula C22H22N2O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Benzenepropanoic acid, .alpha.-[(4,6-dimethyl-2-pyrimidinyl)oxy]-.beta.-methoxy-.beta.-phenyl-, (.alpha.S)-

References

1. Gäbel G, et al. Transplant Proc. 2003 Sep;35(6):2137-8.

2. Witzigmann H, et al. Transplant Proc. 2002 Sep;34(6):2387-8.

3. Vatter H, et al. Cardiovasc Drug Rev. 2006 Spring;24(1):63-76.

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