Chemical Structure : Ambrisentan
CAS No.: 177036-94-1
Catalog No.: PC-43394Not For Human Use, Lab Use Only.
Ambrisentan (BSF 208075, LU 208075) is a highly selective antagonist of the endothelin-1 type A receptor (ETA) for use in the treatment of pulmonary hypertension.
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Ambrisentan (BSF 208075, LU 208075) is a highly selective antagonist of the endothelin-1 type A receptor (ETA) for use in the treatment of pulmonary hypertension.
M.Wt | 378.4211 | |
Formula | C22H22N2O4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Benzenepropanoic acid, .alpha.-[(4,6-dimethyl-2-pyrimidinyl)oxy]-.beta.-methoxy-.beta.-phenyl-, (.alpha.S)- |
1. Gäbel G, et al. Transplant Proc. 2003 Sep;35(6):2137-8.
2. Witzigmann H, et al. Transplant Proc. 2002 Sep;34(6):2387-8.
3. Vatter H, et al. Cardiovasc Drug Rev. 2006 Spring;24(1):63-76.
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