Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-GPCR-Leukotriene Receptor-Amelubant
Amelubant

Chemical Structure : Amelubant

CAS No.: 346735-24-8

Add to Favorites

Amelubant (BIIL 284, BIIL-284)

Catalog No.: PC-63302Not For Human Use, Lab Use Only.

Amelubant (BIIL 284) is a potent, long-acting, orally active leukotriene B4 (LTB4) receptor antagonist with Ki values of 221 nM and 230 nM in vital cells and membranes.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Amelubant (BIIL 284) is a potent, long-acting, orally active leukotriene B4 (LTB4) receptor antagonist with Ki values of 221 nM and 230 nM in vital cells and membranes.
    Amelubant (BIIL 284) inhibits LTB4-induced mouse ear inflammation with ED50 of 0.008 mg/kg (p.o.).
    Amelubant (BIIL 284) inhibits LTB(4)-induced transdermal chemotaxis in guinea pigs with ED50 of 0.03 mg/kg p.o.

    Physicochemical Properties

    M.Wt 538.644
    Formula C33H34N2O5
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    ethyl (Z)-(amino(4-((3-((4-(2-(4-hydroxyphenyl)propan-2-yl)phenoxy)methyl)benzyl)oxy)phenyl)methylene)carbamate

    References

    1. Birke FW, et al. J Pharmacol Exp Ther. 2001 Apr;297(1):458-66.

    2. Döring G, et al. J Cyst Fibros. 2014 Mar;13(2):156-63.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: