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Amiclenomycin

Chemical Structure : Amiclenomycin

CAS No.: 53696-70-1

Amiclenomycin

Catalog No.: PC-25837Not For Human Use, Lab Use Only.

Amiclenomycin is a natural L-amino acid antibiotic that blocks the biosynthesis of biotin by inhibiting 7,8-diaminopelargonic acid synthase (BioA synthase, DAPAS), inhibits growth of microorganisms and is specific against mycobacteria in vitro.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Amiclenomycin is a natural L-amino acid antibiotic that blocks the biosynthesis of biotin by inhibiting 7,8-diaminopelargonic acid synthase (BioA synthase, DAPAS), inhibits growth of microorganisms and is specific against mycobacteria in vitro.

Physicochemical Properties

M.Wt 196.25
Formula C10H16N2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-2-Amino-4-(4-aminocyclohexa-2,5-dien-1-yl)butanoic acid

References

1. Mann S, et al. Chemistry. 2002 Jan 18;8(2):439-50.

2. Sandmark J, et al. J Biol Chem. 2002 Nov 8;277(45):43352-8.

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