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Chemical Structure : Amitifadine
Catalog No.: PC-70169Not For Human Use, Lab Use Only.
A triple monoamine reuptake inhibitor, inhibits the reuptake of 5-HT, norepinephrine and dopamine in HEK 293 cells with IC50 of 12, 23 and 96 nM, respectively.
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A triple monoamine reuptake inhibitor, inhibits the reuptake of 5-HT, norepinephrine and dopamine in HEK 293 cells with IC50 of 12, 23 and 96 nM, respectively; reduces the duration of immobility in the forced swim test in rats with an oral minimum effective dose (MED) of 5 mg/kg.
Depression
Phase 3 Clinical
| M.Wt | 228.118 | |
| Formula | C11H11Cl2N | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Skolnick P, et al. Eur J Pharmacol. 2003 Feb 14;461(2-3):99-104.
2. Warnock KT, et al. Pharmacol Biochem Behav. 2012 Nov;103(1):111-8.
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