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Chemical Structure : Amonafide
CAS No.: 69408-81-7
Catalog No.: PC-42763Not For Human Use, Lab Use Only.
Amonafide (AS1413) is a small molecule topoisomerase II (Topo II) inhibitor and DNA intercalator that induces apoptotic signaling by blocking the binding of Topo II to DNA.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $78 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $228 | In stock | |
| 100 mg | Get quote |
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Amonafide (AS1413) is a small molecule topoisomerase II (Topo II) inhibitor and DNA intercalator that induces apoptotic signaling by blocking the binding of Topo II to DNA.
| M.Wt | 283.3251 | |
| Formula | C16H17N3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1H-Benz[de]isoquinoline-1,3(2H)-dione, 5-amino-2-[2-(dimethylamino)ethyl]- |
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1. Allen SL, et al. Expert Opin Investig Drugs. 2011 Jul;20(7):995-1003.
2. Zhu H, et al. Mol Cancer Ther. 2007 Feb;6(2):484-95.
3. Liang X, et al. Mol Cancer Res. 2010 Dec;8(12):1619-32.
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