Catalog No.: PC-42743Not For Human Use, Lab Use Only.
Ampalex (CX516) is a positive allosteric modulator of AMPA, increases fast, excitatory (glutamatergic) synaptic responses in hippocampal slices by about 50% with an EC50 of 170 uM.
Ampalex (CX516) is a positive allosteric modulator of AMPA, increases fast, excitatory (glutamatergic) synaptic responses in hippocampal slices by about 50% with an EC50 of 170 uM.
Ampalex (CX516) increases the potency of the glutamate concentration-response profile by 3-fold.
Physicochemical Properties
M.Wt
241.2884
Formula
C14H15N3O
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 41 mg/mL
Chemical Name/SMILES
Methanone, 1-piperidinyl-6-quinoxalinyl-
References
1. Arai A, et al. J Pharmacol Exp Ther. 1996 Aug;278(2):627-38.
2. Hampson RE, et al. J Neurosci. 1998 Apr 1;18(7):2740-7.
