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Chemical Structure : Ampalex
CAS No.: 154235-83-3
Catalog No.: PC-42743Not For Human Use, Lab Use Only.
Ampalex (CX516) is a positive allosteric modulator of AMPA, increases fast, excitatory (glutamatergic) synaptic responses in hippocampal slices by about 50% with an EC50 of 170 uM.
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Ampalex (CX516) is a positive allosteric modulator of AMPA, increases fast, excitatory (glutamatergic) synaptic responses in hippocampal slices by about 50% with an EC50 of 170 uM.
Ampalex (CX516) increases the potency of the glutamate concentration-response profile by 3-fold.
| M.Wt | 241.2884 | |
| Formula | C14H15N3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 41 mg/mL |
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| Chemical Name/SMILES |
Methanone, 1-piperidinyl-6-quinoxalinyl- |
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1. Arai A, et al. J Pharmacol Exp Ther. 1996 Aug;278(2):627-38.
2. Hampson RE, et al. J Neurosci. 1998 Apr 1;18(7):2740-7.
3. Baumbarger PJ, et al. J Pharmacol Exp Ther. 2001 Jul;298(1):86-102.
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