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Ampalex

Chemical Structure : Ampalex

CAS No.: 154235-83-3

Ampalex (CX516;BDP 12;Ampakine CX516)

Catalog No.: PC-42743Not For Human Use, Lab Use Only.

A positive allosteric modulator of AMPAR.

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50 mg $80 In stock
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200 mg $168 In stock

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A positive allosteric modulator of AMPAR; increases fast, excitatory (glutamatergic) synaptic responses in hippocampal slices by about 50% with an EC50 of 170 uM; increases the potency of the glutamate concentration-response profile by 3-fold.

Physicochemical Properties

M.Wt 241.2884
Formula C14H15N3O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 41 mg/mL

Chemical Name/SMILES

Methanone, 1-piperidinyl-6-quinoxalinyl-

References

1. Arai A, et al. J Pharmacol Exp Ther. 1996 Aug;278(2):627-38.

2. Hampson RE, et al. J Neurosci. 1998 Apr 1;18(7):2740-7.

3. Baumbarger PJ, et al. J Pharmacol Exp Ther. 2001 Jul;298(1):86-102.

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