Chemical Structure : Amprenavir
CAS No.:
161814-49-9
Amprenavir
(VX-478;141W94;VX478)
Catalog No. : PC-45253Not For Human Use, Lab Use Only.
Amprenavir (VX-478) is a potent HIV-1 protease inhibitor with IC50 of 80 nM, has mean IC50 of 12 nM against 6 HIV clinical isolates.
Packing Price Stock Quantity 25 mg $118 In stock 0 1 2 3 4 5 50 mg $178 In stock 0 1 2 3 4 5 100 mg $278 In stock 0 1 2 3 4 5 250 mg Get quote 0 1 2 3 4 5 1 g Get quote 0 1 2 3 4 5
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4525301
Biological Activity
Amprenavir (VX-478) is a potent HIV-1 protease inhibitor with IC50 of 80 nM, has mean IC50 of 12 nM against 6 HIV clinical isolates.
Physicochemical Properties
M.Wt
505.6269
Formula
C25H35N3O6S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Carbamic acid, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3S)-tetrahydro-3-furanyl ester
References
1. St Clair MH, et al. Antiviral Res. 1996 Jan;29(1):53-6.
2. Partaledis JA, et al. J Virol. 1995 Sep;69(9):5228-35.
3. Markland W, et al. J Virol. 2000 Aug;74(16):7636-41.
Contact Us
sales@probechem.com
