Amylovis-201 | Sigma-1 agonist | Probechem Biochemicals

Chemical Structure : Amylovis-201

Amylovis-201 (CNEURO-201)

Catalog No.: PC-23425Not For Human Use, Lab Use Only.

Amylovis-201 is dual-target ligand acting as an anti-amyloidogenic compound and a potent agonist of the σ1 chaperone protein, interferes with Amyloid-β aggregation.

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Biological Activity

Amylovis-201 is dual-target ligand acting as an anti-amyloidogenic compound and a potent agonist of the σ1 chaperone protein, interferes with Amyloid-β aggregation.

Physicochemical Properties

M.Wt	375.51
Formula	C18H21N3O2S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	methyl (2-(4-(naphthalen-1-ylamino)-4-oxobutanamido)ethyl)carbamodithioate

References

1. García-Pupo L, et al. Acta Pharm Sin B. 2024 Oct;14(10):4345-4359.

2. Rivera-Marrero S., et al. Bioorg Med Chem. 2020;28 doi: 10.1016/j.bmc.2020.115700.

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Amylovis-201 (CNEURO-201)

Biological Activity

Physicochemical Properties

References

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