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Anamorelin hydrochloride

Chemical Structure : Anamorelin hydrochloride

CAS No.: 861998-00-7

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Anamorelin hydrochloride (RC-1291 hydrochloride, ONO-7643 hydrochloride)

Catalog No.: PC-44044Not For Human Use, Lab Use Only.

Anamorelin hydrochloride (RC-1291, ONO-7643) is a non-peptide, centrally-penetrant and selective agonist of GHSR with 50 of 0.74 nM, shows appetite-enhancing and anabolic effects, orally bioactive.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Anamorelin hydrochloride (RC-1291, ONO-7643) is a non-peptide, centrally-penetrant and selective agonist of GHSR with 50 of 0.74 nM, shows appetite-enhancing and anabolic effects, orally bioactive.

Physicochemical Properties

M.Wt 583.1645
Formula C31H43ClN6O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
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Solubility

DMSO: ≥ 28 mg/mL
Chemical Name/SMILES

3-Piperidinecarboxylic acid, 1-[(2R)-2-[(2-amino-2-methyl-1-oxopropyl)amino]-3-(1H-indol-3-yl)-1-oxopropyl]-3-(phenylmethyl)-, 1,2,2-trimethylhydrazide, hydrochloride (1:1), (3R)-

References

1. Northrup R, et al. Support Care Cancer. 2013 Sep;21(9):2409-15.

2. Zhang H, et al. Expert Opin Pharmacother. 2015 Jun;16(8):1245-53.

3. Pietra C, et al. J Cachexia Sarcopenia Muscle. 2014 Dec;5(4):329-37.

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