Catalog No.: PC-42742Not For Human Use, Lab Use Only.
Aniracetam (Ro 13-5057) is a positive allosteric modulator of AMPAR, potentiates the iQA responses induced in Xenopus oocytes by rat brain mRNA in a reversible manner.
Aniracetam (Ro 13-5057) is a positive allosteric modulator of AMPAR, potentiates the iQA responses induced in Xenopus oocytes by rat brain mRNA in a reversible manner.
Aniracetam enhances glutamate-evoked currents in whole-cell recordings.
Aniracetam strongly reduces glutamate receptor desensitization.
Aniracetam selectively prolongs the time course and increases the peak amplitude of fast synaptic currents.
Physicochemical Properties
M.Wt
219.2365
Formula
C12H13NO3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2-Pyrrolidinone, 1-(4-methoxybenzoyl)-
References
1. Ito I, et al. J Physiol. 1990 May;424:533-43.
2. Isaacson JS, et al. Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10936-40.
3. Tang CM, et al. Science. 1991 Oct 11;254(5029):288-90.
