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Aniracetam

Chemical Structure : Aniracetam

CAS No.: 72432-10-1

Aniracetam (Ro 13-5057, Ro13-5057)

Catalog No.: PC-42742Not For Human Use, Lab Use Only.

Aniracetam (Ro 13-5057) is a positive allosteric modulator of AMPAR, potentiates the iQA responses induced in Xenopus oocytes by rat brain mRNA in a reversible manner.

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Biological Activity

Aniracetam (Ro 13-5057) is a positive allosteric modulator of AMPAR, potentiates the iQA responses induced in Xenopus oocytes by rat brain mRNA in a reversible manner.
Aniracetam enhances glutamate-evoked currents in whole-cell recordings.
Aniracetam strongly reduces glutamate receptor desensitization.
Aniracetam selectively prolongs the time course and increases the peak amplitude of fast synaptic currents.

Physicochemical Properties

M.Wt 219.2365
Formula C12H13NO3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-Pyrrolidinone, 1-(4-methoxybenzoyl)-

References

1. Ito I, et al. J Physiol. 1990 May;424:533-43.

2. Isaacson JS, et al. Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10936-40.

3. Tang CM, et al. Science. 1991 Oct 11;254(5029):288-90.

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