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Aniracetam

Chemical Structure : Aniracetam

CAS No.: 72432-10-1

Aniracetam (Ro 13-5057)

Catalog No.: PC-42742Not For Human Use, Lab Use Only.

A positive allosteric modulator of AMPAR.

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Biological Activity

A positive allosteric modulator of AMPAR; potentiates the iQA responses induced in Xenopus oocytes by rat brain mRNA in a reversible manner; enhances glutamate-evoked currents in whole-cell recordings; strongly reduces glutamate receptor desensitization; selectively prolongs the time course and increases the peak amplitude of fast synaptic currents.

Physicochemical Properties

M.Wt 219.2365
Formula C12H13NO3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-Pyrrolidinone, 1-(4-methoxybenzoyl)-

References

1. Ito I, et al. J Physiol. 1990 May;424:533-43.

2. Isaacson JS, et al. Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10936-40.

3. Tang CM, et al. Science. 1991 Oct 11;254(5029):288-90.

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