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Anisomycin

Chemical Structure : Anisomycin

CAS No.: 22862-76-6

Anisomycin (Flagecidin, Wuningmeisu C)

Catalog No.: PC-45586Not For Human Use, Lab Use Only.

Anisomycin (Flagecidin, Wuningmeisu C) is an antibiotic that inhibits eukaryotic protein synthesis by inhibiting peptidyl transferase or the 80S ribosome.

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Biological Activity

Anisomycin (Flagecidin, Wuningmeisu C) is an antibiotic that inhibits eukaryotic protein synthesis by inhibiting peptidyl transferase or the 80S ribosome.
Anisomycin sensitizes RCC cells to DR4-mediated apoptosis through the induction of DR4.

Physicochemical Properties

M.Wt 265.305
Formula C14H19NO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3,4-Pyrrolidinediol, 2-[(4-methoxyphenyl)methyl]-, 3-acetate, (2R,3S,4S)-

References

1. Grollman AP. J Biol Chem. 1967 Jul 10;242(13):3226-33.

2. Li Y, et al. Anticancer Drugs. 2017 Feb;28(2):180-186.

3. Sorg BA, et al. Neuropharmacology. 2015 May;92:25-33.

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