Anlotinib (AL-3818) | Multikinase inhibitor

Chemical Structure : Anlotinib

CAS No.: 1058156-90-3

Anlotinib (AL-3818, AL3818)

Catalog No.: PC-45681Not For Human Use, Lab Use Only.

Anlotinib (AL-3818) is a novel multi-target tyrosine kinase that primarily inhibit VEGFR2/3, FGFR1-4, PDGFR α/β, c-Kit, and Ret.

Packing	Price	Stock
5 mg	$228	In stock
10 mg	$368	In stock
25 mg	$568	In stock
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Biological Activity

Anlotinib (AL-3818) is a novel multi-target tyrosine kinase that primarily inhibit VEGFR2/3, FGFR1-4, PDGFR α/β, c-Kit, and Ret.
Anlotinib (AL-3818) shows antitumor activity against tumor cells carrying mutations in PDGFR α, c-Kit, Met, and epidermal growth factor receptor (EGFR).

Physicochemical Properties

M.Wt	407.4375
Formula	C23H22FN3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 44 mg/mL
Chemical Name/SMILES	Cyclopropanamine, 1-[[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-quinolinyl]oxy]methyl]-

References

1. Sun Y, et al. J Hematol Oncol. 2016 Oct 4;9(1):105.

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Anlotinib (AL-3818, AL3818)

Biological Activity

Physicochemical Properties

References

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