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Apelin receptor agonist cmpd644

Chemical Structure : Apelin receptor agonist cmpd644

CAS No.: 2049973-39-7

Apelin receptor agonist cmpd644

Catalog No.: PC-23721Not For Human Use, Lab Use Only.

Apelin receptor agonist cmpd644 is a potent small-molecule agonist of apelin receptor (APJR).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Apelin receptor agonist cmpd644 is a potent small-molecule agonist of apelin receptor (APJR).

Physicochemical Properties

M.Wt 525.58
Formula C24H27N7O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1S,2R)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methylpyridin-2-yl)-4H-1,2,4-triazol-3-yl)-1-hydroxy-1-(5-methylpyrimidin-2-yl) propane-2-sulfonamide

References

1. Yang Yue, et al. Nat Struct Mol Biol. 2022 Jul;29(7):688-697.

2. US patent WO2016187308A1

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