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Argatroban

Chemical Structure : Argatroban

CAS No.: 74863-84-6

Argatroban (MD-805, MD805)

Catalog No.: PC-23031Not For Human Use, Lab Use Only.

Argatroban (MD-805) is a potent, selective thrombin inhibitor with Ki of 19 nM, binds to the active site of thrombin, thereby preventing fibrin deposition.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Argatroban (MD-805) is a potent, selective thrombin inhibitor with Ki of 19 nM, binds to the active site of thrombin, thereby preventing fibrin deposition.

Physicochemical Properties

M.Wt 508.64
Formula C23H36N6O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2R,4R)-1-((2S)-5-Guanidino-2-(3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamido)pentanoyl)-4-methylpiperidine-2-carboxylic acid

References

1. Kikumoto R, et al. Biochemistry. 1984 Jan 3;23(1):85-90.

2. Matsuo T, et al. Thromb Res. 1986 Oct 15;44(2):247-51.

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