Arglabin | EGFR inhibitor | Probechem Biochemicals

Chemical Structure : Arglabin

CAS No.: 84692-91-1

Arglabin ((+)-Arglabin)

Catalog No.: PC-22843Not For Human Use, Lab Use Only.

Arglabin is a sesquiterpene lactone from the Chinese herb Artemisia myriantha Wall. (Asteraceae), shows anti-inflammatory and antitumor activities, inhibits the EGFR downstream signaling pathways mTORC1 and mTORC2.

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Biological Activity

Physicochemical Properties

M.Wt	246.31
Formula	C15H18O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(3aR,4aS,6aS,9aS,9bR)-1,4a-Dimethyl-7-methylene-5,6,6a,7,9a,9b-hexahydro-3H-oxireno[2',3':8,8a]azuleno[4,5-b]furan-8(4aH)-one

References

1. Bottex-Gauthier C, et al. Biotechnol Ther. 1993;4(1-2):77-98.

2. El Gaafary M, et al. Biomed Pharmacother. 2022 Dec;156:113873.

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Arglabin ((+)-Arglabin)

Biological Activity

Physicochemical Properties

References

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