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Asaretoclax

Chemical Structure : Asaretoclax

CAS No.: 2363074-01-3

Asaretoclax (ZN-d5)

Catalog No.: PC-24935Not For Human Use, Lab Use Only.

Asaretoclax (ZN-d5) is a potent, selective and orally bioavailable inhibitor of the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2), with potential pro-apoptotic and antineoplastic activities.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Asaretoclax (ZN-d5) is a potent, selective and orally bioavailable inhibitor of the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2), with potential pro-apoptotic and antineoplastic activities.

Physicochemical Properties

M.Wt 902.07
Formula C47H57F2N7O7S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzamide, 4-[4-[[2-[3-(difluoromethyl)bicyclo[1.1.1]pent-1-yl]-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(trans-4-hydroxy-4-methylcyclohexyl)methyl]amino]-3-nitrophenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-

References

1. Patent WO2022133446 A1.

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