Aster-A PROTAC NGF3

Chemical Structure : Aster-A PROTAC NGF3

Catalog No.: PC-24732Not For Human Use, Lab Use Only.

Aster-A PROTAC NGF3 is a VHL-based PROTAC degrader of GRAM domain containing 1A (GRAMD1A, Aster-A) with DC50 of 4.8 uM, Dmax=60%, in HeLa cells.

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Biological Activity

Aster-A PROTAC NGF3 is a VHL-based PROTAC degrader of GRAM domain containing 1A (GRAMD1A, Aster-A) with DC50 of 4.8 uM, Dmax=60%, in HeLa cells.

M.Wt	845.97
Formula	C42H51N7O10S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	tert-butyl 2-(4-((3-(4-(3-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)propoxy)butoxy)propyl)carbamoyl)benzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate

1. He N, et al. Bioorg Med Chem. 2024 Apr 1;103:117673.