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Chemical Structure : Asundexian
CAS No.: 2064121-65-7
Catalog No.: PC-73137Not For Human Use, Lab Use Only.
Asundexian (BAY 2433334) a highly potent, selective inhibitor targeting FXIa.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $468 | In stock | |
| 25 mg | $988 | In stock | |
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| 250 mg | Get quote | ||
| 1 g | Get quote |
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Asundexian (BAY 2433334) a highly potent, selective inhibitor targeting FXIa.
Asundexian inhibits human FXIa with high potency and selectivity.
Asundexian reduces FXIa activity, thrombin generation triggered by contact activation or low concentrations of tissue factor, and prolongs activated partial thromboplastin time in human, rabbit and various other species, but not in rodents.
Asundexian reduces thrombus weight in the FeCl2 -injury models.
Asundexian reduces thrombus weight when administered before or during thrombus formation in the AV-shunt model.
| M.Wt | 592.936 | |
| Formula | C26H21ClF4N6O4 | |
| CAS No. | 2064121-65-7 | |
| Storage |
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| Solubility |
100 mM in DMSO (59.3 mg/mL) |
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| Chemical Name |
(S)-4-(2-(4-(5-chloro-2-(4-(trifluoromethyl)-1H-1,2,3-triazol-1-yl)phenyl)-5-methoxy-2-oxopyridin-1(2H)-yl)butanamido)-2-fluorobenzamide |
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1. Stefan Heitmeier, et al. J Thromb Haemost. 2022 Mar 15. doi: 10.1111/jth.15700.
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