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Chemical Structure : At14-3-3 inhibitor 2
Catalog No.: PC-22228Not For Human Use, Lab Use Only.
At14-3-3 inhibitor 2 is a covalent selective inhibitor for Arabidopsis thaliana 14-3-3 protein (At14-3-3), potently inhibits the interaction between At14-3-3 Lambda and FAM-FD with IC50 of 1.2 uM.
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At14-3-3 inhibitor 2 is a covalent selective inhibitor for Arabidopsis thaliana 14-3-3 protein (At14-3-3), potently inhibits the interaction between At14-3-3 Lambda and FAM-FD with IC50 of 1.2 uM.
At14-3-3 inhibitor 2 covalently binds to an allosteric site of 14-3-3 (Cys198) with isoform selectivity.
Infiltration of At14-3-3 inhibitor 2 to Arabidopsis leaves suppressed the stomatal aperture.
| M.Wt | 441.45 | |
| Formula | C22H19NO7S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kotaro Nishiyama, et al. Angew Chem Int Ed Engl. 2024 Apr 24:e202400218.
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