Catalog No.: PC-61607Not For Human Use, Lab Use Only.
Ataciguat (HMR-1766) is a potent, specific soluble guanylate cyclase (sGC) activator with EC50 of 0.51 uM, preferentially activates the NO-insensitive heme-oxidized form of sGC.
Ataciguat (HMR-1766) is a potent, specific soluble guanylate cyclase (sGC) activator with EC50 of 0.51 uM, preferentially activates the NO-insensitive heme-oxidized form of sGC.
Ataciguat (HMR-1766) increases cGMP levels in cultured rat aortic smooth muscle cells.
Ataciguat (HMR-1766) induces vasorelaxation of isolated endothelium-denuded rat aorta, porcine coronary arteries, and human corpus cavernosum with EC50 of 1-10 uM.
Ataciguat (HMR-1766) decreases arterial blood pressure in anesthetized pigs.
