Catalog No.: PC-20903Not For Human Use, Lab Use Only.
Atglistatin is a selective adipose triglyceride lipase (ATGL) inhibitor, inhibits lipolysis in living cells with IC50 of 0.7 uM, directly inhibits ATGL in a competitive manner with Ki of 355 nM.
Atglistatin is a selective adipose triglyceride lipase (ATGL) inhibitor, inhibits lipolysis in living cells with IC50 of 0.7 uM, directly inhibits ATGL in a competitive manner with Ki of 355 nM.
Atglistatin does not inhibit HSL, MGL, pancreatic lipase, lipoprotein lipase, PNPLA6 and PNPLA7.
Atglistatin does not cause cardiac TG accumulation, despite inhibition of lipolysis.
Atglistatin is a tool compound to study the pathophysiology and druggability of ATGL in animal models of metabolic disease and cachexia.
