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Chemical Structure : Atibuclimab
CAS No.:
Catalog No.: PC-Ab1060Not For Human Use, Lab Use Only.
Atibuclimab (IC14) is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis. Human monocyte differentiation antigen CD14 is a pattern recognition receptor (PRR) that enhances innate immune responses. Atibuclimab (IC14) attenuated the LPS-induced release of MIP-1beta, but not of MIP-1alpha. IL-8 and MCP-1, but not MIP-1alpha and MIP-1b, circulate in RBC-associated form during endotoxemia..
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|---|---|---|---|
| 1 mg | $358 | In stock | |
| 5 mg | $758 | In stock | |
| 10 mg | $1280 | In stock | |
| 100 mg | Get quote |
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Atibuclimab (IC14) is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis. Human monocyte differentiation antigen CD14 is a pattern recognition receptor (PRR) that enhances innate immune responses. Atibuclimab (IC14) attenuated the LPS-induced release of MIP-1beta, but not of MIP-1alpha. IL-8 and MCP-1, but not MIP-1alpha and MIP-1b, circulate in RBC-associated form during endotoxemia.
| M.Wt | ||
| Formula | Human IgG4-Kappa | |
| Appearance | Solid | |
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| Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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