Chemical Structure : Atomoxetine hydrochloride
CAS No.: 82248-59-7
Catalog No.: PC-63053Not For Human Use, Lab Use Only.
Atomoxetine hydrochloride((R)-Tomoxetine LY-139603) is a potent, selective norepinephrine (NE) transporter inhibitor with Ki of 5 nM.
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Atomoxetine hydrochloride((R)-Tomoxetine LY-139603) is a potent, selective norepinephrine (NE) transporter inhibitor with Ki of 5 nM.
Atomoxetine shows weak affinity for 5-HT and dopamine transporters with IC50 of 77 and 1,451 nM, respectively.
Atomoxetine has been approved for the treatment of attention deficit hyperactivity disorder (ADHD).
M.Wt | 291.819 | |
Formula | C17H22ClNO | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(3R)-N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine hydrochloride |
1. Bymaster FP, et al. Neuropsychopharmacology. 2002 Nov;27(5):699-711.
2. Sauer JM, et al. Clin Pharmacokinet. 2005;44(6):571-90.
3. Passamonti L, et al. Psychopharmacology (Berl). 2017 Aug;234(15):2289-2297.
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