Chemical Structure : Avanafil
CAS No.: 330784-47-9
Catalog No.: PC-45440Not For Human Use, Lab Use Only.
Avanafil (TA1790) is a potent and highly selective PDE5 inhibitor (IC50=5.2 nM) for erectile dysfunction.
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Avanafil (TA1790) is a potent and highly selective PDE5 inhibitor (IC50=5.2 nM) for erectile dysfunction.
Avanafil (TA1790) shows no significant effect on PDE1, PDE6 and PDE11.
M.Wt | 483.9507 | |
Formula | C23H26ClN7O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
5-Pyrimidinecarboxamide, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)- |
1. Kotera J, et al. J Urol. 2012 Aug;188(2):668-74.
2. Limin M, et al. Expert Opin Investig Drugs. 2010 Nov;19(11):1427-37.
3. Wang R, et al. J Sex Med. 2012 Aug;9(8):2122-9.
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