Avatrombopag | TPO receptor agonist | Probechem Biochemicals

Chemical Structure : Avatrombopag

CAS No.: 570406-98-3

Avatrombopag (AKR-501, E5501, YM477)

Catalog No.: PC-22882Not For Human Use, Lab Use Only.

Avatrombopag (AKR-501, YM477) is a potent, orally active, nonpeptide thrombopoietin (TPO) receptor agonist with EC50 of 3.3 nM, mimics the biological activities of TPO.

Packing	Price	Stock
10 mg	$128	In stock
25 mg	$218	In stock
50 mg	$358	In stock
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Biological Activity

Avatrombopag (AKR-501, YM477) is a potent, orally active, nonpeptide thrombopoietin (TPO) receptor agonist with EC50 of 3.3 nM, mimics the biological activities of TPO.

Physicochemical Properties

M.Wt	649.65
Formula	C29H34Cl2N6O3S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid

References

1. Fukushima-Shintani M, et al. Eur J Haematol. 2009;82(4):247-254.

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Avatrombopag (AKR-501, E5501, YM477)

Biological Activity

Physicochemical Properties

References

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