Chemical Structure : Avatrombopag
CAS No.: 570406-98-3
Catalog No.: PC-22882Not For Human Use, Lab Use Only.
Avatrombopag (AKR-501, YM477) is a potent, orally active, nonpeptide thrombopoietin (TPO) receptor agonist with EC50 of 3.3 nM, mimics the biological activities of TPO.
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Avatrombopag (AKR-501, YM477) is a potent, orally active, nonpeptide thrombopoietin (TPO) receptor agonist with EC50 of 3.3 nM, mimics the biological activities of TPO.
M.Wt | 649.65 | |
Formula | C29H34Cl2N6O3S2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid |
1. Fukushima-Shintani M, et al. Eur J Haematol. 2009;82(4):247-254.
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