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Avatrombopag

Chemical Structure : Avatrombopag

CAS No.: 570406-98-3

Avatrombopag (AKR-501, E5501, YM477)

Catalog No.: PC-22882Not For Human Use, Lab Use Only.

Avatrombopag (AKR-501, YM477) is a potent, orally active, nonpeptide thrombopoietin (TPO) receptor agonist with EC50 of 3.3 nM, mimics the biological activities of TPO.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Avatrombopag (AKR-501, YM477) is a potent, orally active, nonpeptide thrombopoietin (TPO) receptor agonist with EC50 of 3.3 nM, mimics the biological activities of TPO.

Physicochemical Properties

M.Wt 649.65
Formula C29H34Cl2N6O3S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid

References

1. Fukushima-Shintani M, et al. Eur J Haematol. 2009;82(4):247-254.

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