Avexitide | GLP-1R antagonist | Probechem Biochemicals

Chemical Structure : Avexitide

CAS No.: 133514-43-9

Avexitide (Exendin(9-39) amide, Exendin 9-39 amide)

Catalog No.: PC-23574Not For Human Use, Lab Use Only.

Avexitide (Exendin-(9-39)) is a selective glucagon-like peptide 1 receptor (GLP-1R) antagonist, competes with endogenous GLP-1 for binding to GLP-1 receptors with Ki of 4.0 nM.

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Biological Activity

Avexitide (Exendin-(9-39)) is a selective glucagon-like peptide 1 receptor (GLP-1R) antagonist, competes with endogenous GLP-1 for binding to GLP-1 receptors with Ki of 4.0 nM.

Physicochemical Properties

M.Wt	3369.8
Formula	C149H234N40O47S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

References

1. Tan M, et al. Diabetes Obes Metab. 2020 Aug;22(8):1406-1416.

2. Schepp W, et al. Eur J Pharmacol. 1994 Oct 14;269(2):183-91.

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Avexitide (Exendin(9-39) amide, Exendin 9-39 amide)

Biological Activity

Physicochemical Properties

References

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