Azaphilone-9 |CAS:1448460-87-4 Probechem Biochemicals

Chemical Structure : Azaphilone-9

Azaphilone-9 (AZA-9)

Catalog No.: PC-60914Not For Human Use, Lab Use Only.

Azaphilone-9 is a fungal natural product that binds to HuR and inhibits HuR-RNA interaction in vitro with IC50 of 1.2 uM.

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Biological Activity

Azaphilone-9 is a fungal natural product that binds to HuR and inhibits HuR-RNA interaction in vitro with IC50 of 1.2 uM.
Azaphilone-9 inhibits HuR-AU-rich elements (ARE) interaction and blocks key RNA-binding residues of HuR.

Physicochemical Properties

M.Wt	435.314
Formula	C21H23BrO5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-bromo-3-((S,1E,3E)-3,5-dimethylhepta-1,3-dien-1-yl)-7-methyl-6,8-dioxo-7,8-dihydro-6H-isochromen-7-yl acetate

References

1. Kaur K, et al. PLoS One. 2017 Apr 17;12(4):e0175471.

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Azaphilone-9 (AZA-9)

Biological Activity

Physicochemical Properties

References

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