Chemical Structure : Azenosertib
CAS No.: 2376146-48-2
Catalog No.: PC-72320Not For Human Use, Lab Use Only.
Azenosertib (ZN-c3, Wee1 inhibitor ZN-c33) is a highly potent, selective Wee1 inhibitor with IC50 of 3.8 nM.
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Azenosertib (ZN-c3, Wee1 inhibitor ZN-c33) is a highly potent, selective Wee1 inhibitor with IC50 of 3.8 nM.
ZN-c3 showed excellent in vivo efficacy and is currently being evaluated in phase 2 clinical trials.
M.Wt | 526.645 | |
Formula | C29H34N8O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(R)-2-allyl-1-(7-ethyl-7-hydroxy-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)-6-((4-(4-methylpiperazin-1-yl)phenyl)amino)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one |
1. Peter Q Huang, et al. J Med Chem. 2021 Sep 9;64(17):13004-13024.
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